The Clinical Endocannabinoid System Consortium (CESC) is dedicated to the data & analysis necessary to validate Cannabis products for the benefit of a global marketplace.
CESC curates real-world data In collaboration with a vetted group of scientific professionals, including physicians, chemists, biologists, botanists, engineers, economists, and regulatory affairs specialists. Our approach is informed by biotechnology and influenced by multivariate analysis (AI).
We pursue potency, dosage, and efficacy for product safety validation and clinical correlation. Our efforts are informed by the Cannabis used in active communities.
Initiatives
The Dosing Project: Dose-effect relationships of multi-agent botanicals involve appropriate characterization and categorization of products actively used by consumers. This post-market surveillance study of Cannabis products includes dosage (mg/kg), therapeutic and wellness indications, and an evaluation for adverse events.
The Cannabis Mind: Cannabis use results in a broad range of psychoactive states. From altered consciousness, to energetic, sedative, focused, aroused, creative, and many more, we map the Cannabis mind using subjective scales and Quantitative EEG as a biomarker.
Agronomy: CESC’s focus corroborates appellations, water conservation best practices, remote monitoring, and soil remediation. Our Investigations in breeding, cultivation, and safer pest management techniques support a more sustainable Cannabis industry.
Nomenclature: Quality assurance and predictable effects start with Cannabis characterization and categorization. CESC applies untargeted laboratory analysis to appropriately characterize botanicals and develops algorithms to categorize Cannabis chemotype. Products are further characterized with in vitro cell-based potency bioassays and presented using consumer-focused product labeling.
Cannabis & Immunity: Interactions of Cannabis use and cellular & humoral immune responses
with a focus on improved outcomes in malignant, autoimmune, and infectious disorders.
Capabilities
Analytical Validation: Laboratory characterization of botanical compounds for consistency, stability, and effectiveness.
Good Manufacturing Practices (GMP): Process definition & development; implementing Quality Management Systems; reviewing & certifying Compliance Programs.
Contract Research Organization (CRO): Executing clinical studies; selecting & monitoring sites; recruiting respondents from Cannabis using communities; analyzing & interpreting data for timely and cost-effective commercialization.
Education: Targeting the professional medical community; establishing practice standards; publishing categorical product reports.
The CESC’s broad approach & expertise guide our partners through all phases of the development life cycle: from concept to commercialization.
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